Steve Diamond has named his final XV of the season to take on London Irish on Saturday 10th May at 3.15pm.
Both Henry Thomas and James Gaskell start in what will be their last game in a Sharks shirt.
The team sees six changes to the one that faced Leicester Tigers last Saturday at the AJ Bell Stadium. This includes a complete change to the front row, with Ross Harrison, Tommy Taylor and Henry Thomas in for Eifion Lewis-Roberts, Marc Jones and Vadim Cobilas.
Elsewhere, neither Dwayne Peel or Danny Cipriani feature in the travelling squad, with Will Cliff and Joe Ford taking up their places in the starting line-up respectively.
Mark Easter takes up Viliami Fihaki's spot, who starts the game on the bench, and Dave Seymour continues his skipper role in place of injured captain Dan Braid.
The team is as follows: Starting XV
15 - Tom Arscott, 14 - Tom Brady, 13 - Jonny Leota, 12 - Sammy Tuitupou, 11 - Charlie Ingall, 10 - Joe Ford, 9 - Will Cliff
1 - Ross Harrison, 2 - Tommy Taylor, 3 - Henry Thomas, 4 - Andrei Ostrikov, 5 - Michael Paterson, 6 - Mark Easter, 7 - David Seymour (C), 8 - James Gaskell
16 - Marc Jones, 17 - Eifion Lewis Roberts, 18 - Vadim Cobilas, 19 - Kirill Kulemin, 20 - Viliami Fahiki, 21 - Nathan Fowles, 22 - Nick Macleod, 23 - Mark Jennings
For the full match overview, including stats about previous fixtures and the formation click here
Sale Sharks' European campaign this season has been a case of what might have been but back-row forward Mark Easter insists he and his teammates can hold their heads high even if it ends without a win.
Danny Cipriani has been called up to the England EPS Squad ahead of this season's Six Nations, and Ross Harrison has been called up for the England Saxons squad for their match against Irish Wolfhounds on Friday 30th January.
Steve Diamond has admitted that the experience of this season's European Rugby Champions Cup has made him and his squad even more determined to finish in the Top Six of the Aviva Premiership and so book their passage into next season's European showpiece.
Sharks were left empty handed after a tremendous effort against Clermont Auvergne in appalling conditions at the AJ Bell Stadium. So close but yet so far in the home games in the competition with Steve Diamond's men running Munster,Saracens and Clermont right to the bell on each game.