Sunday sees two games in the Thames Valley, with the Welsh facing Saracens and the Wasps receiving Worcester.
Here are the facts & figures ahead of next weekend:
Sale Sharks v Leicester Tigers (Friday, 8.00pm)
Sale Sharks kick off the weekend's action at Salford City Stadium, seeking their first victory of the new Aviva Premiership Rugby season. After a draw against Leinster in the stadium opener, Sharks gained a bonus point in the sun against Saracens, then disappointed in the rain against London Welsh.
Leicester Tigers got back to winning ways with Saturday's 30-8 defeat of Exeter Chiefs at Welford Road. The Tigers have lost just once away from home in the Premiership in the last twelve months: 11-19 at Exeter on 11th February.
Leicester have won their last five encounters with the Sharks.
Gloucester Rugby v Bath Rugby (Saturday, 2.15pm)
Gloucester Rugby are unbeaten in their last four Aviva Premiership Rugby matches since their opening day defeat at home to table topping Northampton. Gloucester ended a four game losing streak at Kingsholm with their 29-22 victory over Wasps in round four.
Bath Rugby recorded a 31-10 win over Sale Sharks on Saturday to end a run of two successive defeats. Bath's solo win in their last five away trips was 24-23 at Worcester on 1st September.
Bath have been victorious just once in their last nine clashes with the Cherry & Whites: 24-8 at The Rec. on 27th December 2009. Bath have not beaten Gloucester at Kingsholm since 25th February 2006.
Exeter Chiefs v Harlequins (Saturday, 3.00pm)
Exeter Chiefs' only win in their last four Aviva Premiership Rugby fixtures was 14-12 at home to Saracens a fortnight ago, whilst the Chiefs' only defeat at Sandy Park since February was 15-18 to Northampton Saints on 22nd April.
Harlequins' seven-game winning run in the Premiership came to a halt at home to Saracens on
Sunday. Quins are unbeaten in their last five away games in the tournament.
The Chiefs' only win so far over Harlequins in the Premiership came at Sandy Park on 12th February 2011.
London Irish v Northampton Saints (Saturday, 3.00pm)
London Irish's shaky start to the new Aviva Premiership Rugby campaign continued on Friday with their 11-35 reversal at Worcester Warriors. The Exiles have won two of their last three games at Madejski Stadium.
Northampton Saints are the only side in the Premiership with a 100% winning record after five rounds. The Saints have won their last four regular season away games in the competition.
The last three encounters between the two teams have all been won by the away side on the day, whilst Northampton have won on their last three visits to Madejski Stadium.
London Welsh v Saracens (Sunday, 2.15pm)
London Welsh's two game winning run narrowly came to an end at home to Gloucester on Sunday with their 25-31 defeat, the visitors gaining the decisive score with just six minutes left.
Saracens handed defending Aviva Premiership Rugby champions, Harlequins, their first defeat of the new campaign at The Stoop on Sunday, but have now for the first time in their Premiership history gone three whole games without scoring a try.
The two clubs have not met in a competitive match since a Division Two encounter at Bramley Road on 22nd October 1988, which Saracens won 37-4.
London Wasps v Worcester Warriors (Sunday, 3.00pm)
London Wasps' single victory in their last nine matches in all competitions remains the 43-14 win over London Irish at Adams Park in round three of Aviva Premiership Rugby.
Worcester Warriors opened their winning account this season with their 35-11 win over London Irish at Sixways on Friday. The Warriors have slipped to nine successive away defeats in all competitions since the last time they visited Adams Park on New Year's Day and won 6-0.
Both encounters between the clubs in the Premiership last season ended in wins for the away side, whilst the Warriors have been victorious in two of their last three visits to Adams Park.
Our next Aviva Premiership home game will be on Friday 5th October against Leicester Tigers. Click here to book your tickets online, or call 08444 994 994.
