Sale Sharks face London Irish for the second successive weekend, but this time at Reading's Madejski Stadium on Sunday afternoon. They follow this game up by receiving Saracens at Salford City Stadium on Friday, 16th November (kick off 8.00pm).
Games against Scarlets (home) and London Wasps (away) follow in January and February, dates to be confirmed after the first two rounds.
Each Pool provides a winner to take part in the semi finals, planned for the weekend of March 8/9/10th. The Final will be at Worcester's Sixways Stadium on March 17th.
Teams in Pool 1 play games against teams in Pool 4, whilst the teams in Sale Sharks' Pool 2 face the sides in Pool 3.
Pool 1 - Harlequins, Exeter Chiefs, Gloucester Rugby, Newport Gwent Dragons
Pool 2 - Leicester Tigers, Sale Sharks, Worcester Warriors, Cardiff Blues
Pool 3 - Saracens, London Irish, London Wasps, Scarlets
Pool 4 - Northampton Saints, Bath Rugby, London Welsh, Ospreys
Round 1 Fixtures
Friday, 9th November
Cardiff Blues v London Wasps (7.30pm)
Ospreys v Gloucester Rugby (7.45pm)
Saracens v Leicester Tigers (7.45pm)
Saturday, 10th November
Northampton Saints v Harlequins (1.00pm)
Bath Rugby v Newport Gwent Dragons (2.15pm)
Worcester Warriors v Scarlets (3.00pm)
Sunday, 11th November
London Irish v Sale Sharks (3.00pm)
London Welsh v Exeter Chiefs (4.00pm)