A dominant first-half performance saw Cavaliers score five tries before the break to give them a big lead.
Cavaliers got off to a flier when some neat passing play from the backs saw Watkins race through to touch down beneath the posts and Elliott Davies added the extras.
Just two minutes later, another flowing Cavaliers move was started and finished by scrum-half Su'a after some good work from James Stephenson on the right.
The home side were then penalised in front of goal for holding on to the ball and Jets fly-half Nathan Fowles made no mistake with the kick.
Cavaliers responded immediately and after exerting pressure on the Sale pack, Harry Casson powered over in the far left-hand corner.
Fowles had another penalty opportunity for Jets but his second kick of the night fell short of the posts.
Cavaliers earned a penalty which led to Su'a crashing over for his second try and Davies slotted the conversion.
Sale then went on the offence but solid tackling and defending from Cavaliers prevented the visitors from going over the whitewash.
More slick movement from the Worcester backs almost finished with another Watkins try but Cavaliers recycled the ball to set-up Grove to mark his return with a score.
Cavaliers made five changes at the break and Sale immediately bounced back when James Mitchell crashed over the tryline.
Jon Clarke produced a fine show of power and determination to break the Sale backline once again and De Cothi went over allowing Tiff Eden to add the extras.
Warriors continued to threaten but Sale replied with a Sam Bedlow try and Mitchell kicked the conversion.
A fantastic run from Max Stelling saw the centre kick for the corner and although the ball appeared to be going out of play, it bounced off the corner flag and Stephenson was there to seize the opportunity.
Tom Holmes was sent to the sin bin for Sale with just several minutes remaining and South African Dean Hammond rounded off a fantastic evening for the Cavaliers finishing off a superb run down the left wing.
A fine kick from Eden ensured the hosts reached 50 points