Taylor Prell - try
Tom Bulloch - try
Cameron Ledley - try
Nick Rawsthorne - 3 conversions
Harry Wales, Taylor Prell, Tom Bulloch and Cameron Ledley all crossed for Leeds, with Andy Hughes claiming Sale's solitary score.
It may have been a disappointing night for a side mainly filled with under 18's, but Sharks' coaching staff will hope that they can recover mentally from a gruelling defeat.
Sale were breached just eight minutes into the game, when a superb solo run from his own ten metre line by Prell was almost thwarted, only for a loose ball to be picked up and grounded by Wales.
The Yorkshire men added to their tally ten minutes later when Prell profited from good work between Raffeno Cherrington and Charlie Capps to twist and turn past the onrushing defence to cross.
Brendan Thomas' men were struggling to get a stranglehold on the game, and didn't retain enough ball to carry a consistent threat.
Bulloch carried on Carnegie's dream start, with Sharks in danger of letting the game get away from them before half time was up. Nick Rawsthorne's conversion meant Sale had a 21 point gap to chase in the second half.
Things went from bad to worse after the interval though, as Ledley held off the attention of two Sharks players to power over after a quick tap from scrum half Jimmy McDaniels.
There were some bright moments for Sale's youth products. James Mitchell, who has been knocking on the door of the senior squad with some sparkling form, did his best to drive the team on from scrum half, but it was to no avail.
Hughes did manage to get the Sharks on the score-sheet though, winning a scramble on the line to at least give Sale a crumb of comfort.
There was not much to cheer for by the end, but Thomas will hope that playing at the AJ Bell stadium will give some vital experience to his young charges.