Katy Daley Mclean makes six changes to the starting XV scheduled to face Saracens in December.
Katana Howard shifts to a playmaker role and starts at fly-half following a series of impressive performances from 12.
The only other change to the backline is the return of Vicky A Irwin at fullback, with Irish international Lauren Delany shifting to wing.
In the forwards, Catie Benson replaces Gwenllian Pyrs at loosehead prop, with fellow US Eagle Nick James starting alongside Molly Kelly who returns at hooker.
Beth Stafford captains from the second row alongside Molly Morrissey who started in Sharks’ last game against Loughborough.
Finally, in the back-row, Daisy Hibbert-Jones replaces Rachel McLachlan, continuing her impressive comeback from injury.
15. Vicky A Irwin, 14. Lauren Delany, 13. Hollie Bawden, 12. Laura Perrin, 11. Lisa Neumann, 10. Katana Howard, 9. Mhairi Grieve; 1. Catie Benson, 2. Molly Kelly, 3. Nick James, 4. Beth Stafford, 5. Molly Morrissey, 6. Daisy Hibbert-Jones, 7. Georgie Perris-Redding, 8. Vicky E Irwin
16. Elis Martin, 17. Gwenllian Pyrs, 18. Aisha A Marzouq, 19. Nicola Howat, 20. Lucy Winter, 21. Jess Roberts, 22. Lizzie Duffy, 23. Rachel Woosey